Keep the seal on after packing with new grease and they'll be perfectly fine. Waste of time and grease filling that entire wheel hub with grease IMO. (For normal intended use anyway)
However, If you're "4 wheel'n" with it through the swamps and puddles every week then I would recommend removing the inner seals and flushing them out with new grease through the zerk. Mowing the lawn or towing a trailer, not so much.
We have the technology they didn't have back in the day with the seals, so use them until they fail many years down the road and let your grandchildren replace them when necessary.
(Stay away from the stamped steel bearings sealed or not )